In order to treat Myocarditis, the specific cause must be identified. Cultures, biopsies, electrocardiograms, echocardiograms - any or all may be used to determine the reason for inflammation.

There is no direct treatment for Myocarditis. However, antibiotics may reduce the inflammation in cases of bacterial infection. The symptoms may be treated with analgesics and anti-inflammatory drugs, such as steroids and gamma globulin. Medications to treat irregular heartbeats (arrhythmias) may also be necessary. If there is heart block, a temporary artificial pacemaker may be used. Also, blood thinners (anticoagulants) may be prescribed to reduce the risk of blood clots.

To reduce the strain on the heart, bed rest is often required, and oxygen may be given in cases of congestive heart failure. A low sodium diet may also be prescribed.

In very severe cases, involving fulminant (sudden and severe) heart failure, which is fatal if left untreated, mechanical circulatory support with a left ventricular assist device or extracorporeal membrane oxygenation (ECMO) may be necessary.  If heart function does not recover enough to remove mechanical support, a heart transplant may be necessary.

The recovery time and risk of complications from Myocarditis depends on its cause. In most cases, however, complete recovery may be expected.